Preparation Poly(lactide-co-glycolide) Microsphere of Bone Sialoprotein
نویسندگان
چکیده
منابع مشابه
Polylactide-co-glycolide fiber-reinforced calcium phosphate bone cement.
OBJECTIVE To compare the strength of polylactide-co-glycolide fiber-reinforced calcium phosphate bone cement (FRC) with nonreinforced calcium phosphate bone cement (NRC) subjected to simulated dural pulsations in defects larger than 25 cm(2). METHODS Seven NRC and 7 FRC specimens were set in both medium (37.5 cm(2)) and large (50.0 cm(2)) model skull defects while subjected to simulated dural...
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Polymer based nanoparticle formulations have been shown to increase drug bioavailability and/or reduce drug adverse effects. Nonsteroidal anti-inflammatory drugs (e.g. celecoxib) reduce prostaglandin synthesis and cause side effects such as gastrointestinal and renal complications. The aim of this study was to formulate celecoxib entrapped poly lactide-co-glycolide based nanoparticles through a...
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BACKGROUND Celecoxib, a cyclo-oxygenase (COX)-2 inhibitor, has been reported to mediate growth inhibitory effects and to induce apoptosis in various cancer cell lines. In this study, we examined the potential effects of celecoxib on glioma cell proliferation, migration, and inhibition of COX-2 expression in vitro. METHODS Celecoxib was incorporated into poly DL-lactide-co-glycolide (PLGA) nan...
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The objective of this study was to synthesize and characterize novel three-dimensional porous scaffolds made of poly(lactic-co-glycolic acid) (PLGA)/nano-TiO(2)-particle composite microspheres for potential bone repair applications. The introduction of TiO(2) component has been proven capable of largely enhancing mechanical properties of PLGA/TiO(2) microsphere-sintered scaffold ("PLGA/TiO(2)-S...
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ژورنال
عنوان ژورنال: Nano Biomedicine and Engineering
سال: 2010
ISSN: 2150-5578
DOI: 10.5101/nbe.v2i2.p133-137